Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum

SUMMARY: Pyoderma gangrenosum (PG) is an inflammatory disease characterized by sterile infiltration of the skin by neutrophils. We describe a case of a 63-year-old woman who developed PG following an abdominal wall reconstruction. Her initial presentation was thought to be consistent with a surgical...

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Autores principales: Berlinrut, Ilan, Bhatia, Nitasha, Josse, Jonathan M., de Vinck, David, Kaul, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2014
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174238/
https://www.ncbi.nlm.nih.gov/pubmed/25289359
http://dx.doi.org/10.1097/GOX.0000000000000114
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author Berlinrut, Ilan
Bhatia, Nitasha
Josse, Jonathan M.
de Vinck, David
Kaul, Sanjeev
author_facet Berlinrut, Ilan
Bhatia, Nitasha
Josse, Jonathan M.
de Vinck, David
Kaul, Sanjeev
author_sort Berlinrut, Ilan
collection PubMed
description SUMMARY: Pyoderma gangrenosum (PG) is an inflammatory disease characterized by sterile infiltration of the skin by neutrophils. We describe a case of a 63-year-old woman who developed PG following an abdominal wall reconstruction. Her initial presentation was thought to be consistent with a surgical site infection. Antibiotic therapy was initiated, and the patient was taken for multiple irrigation/lavage of her abdomen and debridement of necrotic tissue. Wound cultures remained negative, and maximal antibiotic coverage did not halt tissue breakdown. A trial of steroids was initiated, and the patient’s condition subsequently improved. Tissue biopsy results were compatible with the diagnosis of PG.
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spelling pubmed-41742382014-10-06 Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum Berlinrut, Ilan Bhatia, Nitasha Josse, Jonathan M. de Vinck, David Kaul, Sanjeev Plast Reconstr Surg Glob Open Case Reports SUMMARY: Pyoderma gangrenosum (PG) is an inflammatory disease characterized by sterile infiltration of the skin by neutrophils. We describe a case of a 63-year-old woman who developed PG following an abdominal wall reconstruction. Her initial presentation was thought to be consistent with a surgical site infection. Antibiotic therapy was initiated, and the patient was taken for multiple irrigation/lavage of her abdomen and debridement of necrotic tissue. Wound cultures remained negative, and maximal antibiotic coverage did not halt tissue breakdown. A trial of steroids was initiated, and the patient’s condition subsequently improved. Tissue biopsy results were compatible with the diagnosis of PG. Wolters Kluwer Health 2014-07-09 /pmc/articles/PMC4174238/ /pubmed/25289359 http://dx.doi.org/10.1097/GOX.0000000000000114 Text en Copyright © 2014 The Authors. Published by Lippincott Williams & Wilkins on behalf of The American Society of Plastic Surgeons. PRS Global Open is a publication of the American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Case Reports
Berlinrut, Ilan
Bhatia, Nitasha
Josse, Jonathan M.
de Vinck, David
Kaul, Sanjeev
Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum
title Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum
title_full Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum
title_fullStr Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum
title_full_unstemmed Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum
title_short Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum
title_sort untreatable surgical site infection: consider pyoderma gangrenosum
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174238/
https://www.ncbi.nlm.nih.gov/pubmed/25289359
http://dx.doi.org/10.1097/GOX.0000000000000114
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