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Ceruloplasmin potentiates nitric oxide synthase activity and cytokine secretion in activated microglia

BACKGROUND: Ceruloplasmin is a ferroxidase expressed in the central nervous system both as soluble form in the cerebrospinal fluid (CSF) and as membrane-bound GPI-anchored isoform on astrocytes, where it plays a role in iron homeostasis and antioxidant defense. It has been proposed that ceruloplasmi...

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Detalles Bibliográficos
Autores principales:	Lazzaro, Massimo, Bettegazzi, Barbara, Barbariga, Marco, Codazzi, Franca, Zacchetti, Daniele, Alessio, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174266/ https://www.ncbi.nlm.nih.gov/pubmed/25224679 http://dx.doi.org/10.1186/s12974-014-0164-9

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