The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) eliminates different classes of mRNA substrates including transcripts with long 3′ UTRs. Current models of NMD suggest that the long physical distance between the poly(A) tail and the termination codon reduces the interaction between cytoplasmic poly(A)-binding pro...

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Detalles Bibliográficos
Autores principales: Fatscher, Tobias, Boehm, Volker, Weiche, Benjamin, Gehring, Niels H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174440/
https://www.ncbi.nlm.nih.gov/pubmed/25147240
http://dx.doi.org/10.1261/rna.044933.114

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