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A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer
Mutations affecting mitochondrial complex I, a multi-subunit assembly that couples electron transfer to proton pumping, are the most frequent cause of heritable mitochondrial diseases. However, the mechanisms by which complex I dysfunction results in disease remain unclear. Here, we describe a Droso...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174527/ https://www.ncbi.nlm.nih.gov/pubmed/25085991 http://dx.doi.org/10.1242/dmm.015321 |