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Toll-Like Receptor Signaling Pathways

Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing pathogen-associated molecular patterns derived from various microbes. TLRs signal through the recruitment of specific adaptor molecules, leading to activation of the transcription factors NF-κB and IRFs, which d...

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Detalles Bibliográficos
Autores principales: Kawasaki, Takumi, Kawai, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174766/
https://www.ncbi.nlm.nih.gov/pubmed/25309543
http://dx.doi.org/10.3389/fimmu.2014.00461