Cargando…
The Many Unknowns Concerning the Bioenergetics of Exhaustion and Senescence during Chronic Viral Infection
The immune system cannot be continuously reactivated throughout the lifetime of an organism; there is a finite point at which repeated antigenic challenge leads to the loss of lymphocyte function or the cells themselves. Antigen-specific T cells can be compromised in two ways through the distinct pr...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174864/ https://www.ncbi.nlm.nih.gov/pubmed/25309548 http://dx.doi.org/10.3389/fimmu.2014.00468 |