Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functi...

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Detalles Bibliográficos
Autores principales: Lee, Ho-Hsien, Cherni, Irene, Yu, HongQi, Fromme, Raimund, Doran, Jeffrey D., Grotjohann, Ingo, Mittman, Michele, Basu, Shibom, Deb, Arpan, Dörner, Katerina, Aquila, Andrew, Barty, Anton, Boutet, Sébastien, Chapman, Henry N., Doak, R. Bruce, Hunter, Mark S., James, Daniel, Kirian, Richard A., Kupitz, Christopher, Lawrence, Robert M., Liu, Haiguang, Nass, Karol, Schlichting, Ilme, Schmidt, Kevin E., Seibert, M. Marvin, Shoeman, Robert L., Spence, John C. H., Stellato, Francesco, Weierstall, Uwe, Williams, Garth J., Yoon, Chunhong, Wang, Dingjie, Zatsepin, Nadia A., Hogue, Brenda G., Matoba, Nobuyuki, Fromme, Petra, Mor, Tsafrir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174873/
https://www.ncbi.nlm.nih.gov/pubmed/25295172
http://dx.doi.org/10.1107/S2052252514014900

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