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Inhibition of a TREK-like K(+) channel current by noradrenaline requires both β(1)- and β(2)-adrenoceptors in rat atrial myocytes

AIMS: Noradrenaline plays an important role in the modulation of atrial electrophysiology. However, the identity of the modulated channels, their mechanisms of modulation, and their role in the action potential remain unclear. This study aimed to investigate the noradrenergic modulation of an atrial...

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Detalles Bibliográficos
Autores principales: Bond, Richard C., Choisy, Stéphanie C.M., Bryant, Simon M., Hancox, Jules C., James, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174890/
https://www.ncbi.nlm.nih.gov/pubmed/25205295
http://dx.doi.org/10.1093/cvr/cvu192