Cargando…

Identification of a Novel Gene for Diabetic Traits in Rats, Mice, and Humans

The genetic basis of type 2 diabetes remains incompletely defined despite the use of multiple genetic strategies. Multiparental populations such as heterogeneous stocks (HS) facilitate gene discovery by allowing fine mapping to only a few megabases, significantly decreasing the number of potential c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsaih, Shirng-Wern, Holl, Katie, Jia, Shuang, Kaldunski, Mary, Tschannen, Michael, He, Hong, Andrae, Jaime Wendt, Li, Shun-Hua, Stoddard, Alex, Wiederhold, Andrew, Parrington, John, Ruas da Silva, Margarida, Galione, Antony, Meigs, James, Hoffmann, Raymond G., Simpson, Pippa, Jacob, Howard, Hessner, Martin, Solberg Woods, Leah C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2014
Materias:	Multiparental Populations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174929/ https://www.ncbi.nlm.nih.gov/pubmed/25236446 http://dx.doi.org/10.1534/genetics.114.162982

Ejemplares similares

Genome-Wide Analysis of Grain Yield Stability and Environmental Interactions in a Multiparental Soybean Population
por: Xavier, Alencar, et al.
Publicado: (2017)

Genetic Architecture of Soybean Yield and Agronomic Traits
por: Diers, Brian W., et al.
Publicado: (2018)

Bayesian Modeling of Haplotype Effects in Multiparent Populations
por: Zhang, Zhaojun, et al.
Publicado: (2014)

RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations
por: Munger, Steven C., et al.
Publicado: (2014)

Rapid Identification of Major-Effect Genes Using the Collaborative Cross
por: Ram, Ramesh, et al.
Publicado: (2014)

Whole-Genome Analysis of Multienvironment or Multitrait QTL in MAGIC
por: Verbyla, Arūnas P., et al.
Publicado: (2014)

Adult Plant Development in Triticale (× Triticosecale Wittmack) Is Controlled by Dynamic Genetic Patterns of Regulation
por: Würschum, Tobias, et al.
Publicado: (2014)

Multiparental Mapping of Plant Height and Flowering Time QTL in Partially Isogenic Sorghum Families
por: Higgins, R. H., et al.
Publicado: (2014)

An Eight-Parent Multiparent Advanced Generation Inter-Cross Population for Winter-Sown Wheat: Creation, Properties, and Validation
por: Mackay, Ian J., et al.
Publicado: (2014)

The Genetic Architecture of Maize (Zea mays L.) Kernel Weight Determination
por: Prado, Santiago Alvarez, et al.
Publicado: (2014)

Quantitative Trait Locus Mapping Methods for Diversity Outbred Mice
por: Gatti, Daniel M., et al.
Publicado: (2014)

Fine-Mapping the Wheat Snn1 Locus Conferring Sensitivity to the Parastagonospora nodorum Necrotrophic Effector SnTox1 Using an Eight Founder Multiparent Advanced Generation Inter-Cross Population
por: Cockram, James, et al.
Publicado: (2015)

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis
por: Smallwood, Tangi L., et al.
Publicado: (2014)

Modeling X-Linked Ancestral Origins in Multiparental Populations
por: Zheng, Chaozhi
Publicado: (2015)

Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection
por: Chesler, Elissa J., et al.
Publicado: (2016)

Genetic Analysis of Kernel Traits in Maize-Teosinte Introgression Populations
por: Liu, Zhengbin, et al.
Publicado: (2016)

A Genomic Reference Panel for Drosophila serrata
por: Reddiex, Adam J., et al.
Publicado: (2018)

Linkage Analysis and Association Mapping QTL Detection Models for Hybrids Between Multiparental Populations from Two Heterotic Groups: Application to Biomass Production in Maize (Zea mays L.)
por: Giraud, Héloïse, et al.
Publicado: (2017)

Mating Design and Genetic Structure of a Multi-Parent Advanced Generation Intercross (MAGIC) Population of Sorghum (Sorghum bicolor (L.) Moench)
por: Ongom, Patrick O., et al.
Publicado: (2017)

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice
por: Maurizio, Paul L., et al.
Publicado: (2017)

Joint Analysis of Strain and Parent-of-Origin Effects for Recombinant Inbred Intercrosses Generated from Multiparent Populations with the Collaborative Cross as an Example
por: Liu, Yanyan, et al.
Publicado: (2017)

Dissecting the Genetic Architecture of Shoot Growth in Carrot (Daucus carota L.) Using a Diallel Mating Design
por: Turner, Sarah D., et al.
Publicado: (2017)

Genotyping by Sequencing of 393 Sorghum bicolor BTx623 × IS3620C Recombinant Inbred Lines Improves Sensitivity and Resolution of QTL Detection
por: Kong, WenQian, et al.
Publicado: (2018)

Genetic Loci Governing Androgenic Capacity in Perennial Ryegrass (Lolium perenne L.)
por: Begheyn, Rachel F., et al.
Publicado: (2018)

Identification of Candidate Genes Controlling Black Seed Coat and Pod Tip Color in Cowpea (Vigna unguiculata [L.] Walp)
por: Herniter, Ira A., et al.
Publicado: (2018)

Coping-Style Behavior Identified by a Survey of Parent-of-Origin Effects in the Rat
por: Mont, Carme, et al.
Publicado: (2018)

Recursive Algorithms for Modeling Genomic Ancestral Origins in a Fixed Pedigree
por: Zheng, Chaozhi, et al.
Publicado: (2018)

Empirical Comparisons of Different Statistical Models To Identify and Validate Kernel Row Number-Associated Variants from Structured Multi-parent Mapping Populations of Maize
por: Yang, Jinliang, et al.
Publicado: (2018)

Discovery of QTL Alleles for Grain Shape in the Japan-MAGIC Rice Population Using Haplotype Information
por: Ogawa, Daisuke, et al.
Publicado: (2018)

Genetic Dissection of Resistance to the Three Fungal Plant Pathogens Blumeria graminis, Zymoseptoria tritici, and Pyrenophora tritici-repentis Using a Multiparental Winter Wheat Population
por: Stadlmeier, Melanie, et al.
Publicado: (2019)

Cleaning Genotype Data from Diversity Outbred Mice
por: Broman, Karl W., et al.
Publicado: (2019)

A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size
por: Shorter, John R., et al.
Publicado: (2019)

Determinants of QTL Mapping Power in the Realized Collaborative Cross
por: Keele, Gregory R., et al.
Publicado: (2019)

Whole Genome Sequencing and Progress Toward Full Inbreeding of the Mouse Collaborative Cross Population
por: Shorter, John R., et al.
Publicado: (2019)

Testing Pleiotropy vs. Separate QTL in Multiparental Populations
por: Boehm, Frederick J., et al.
Publicado: (2019)

Inbred Strain Variant Database (ISVdb): A Repository for Probabilistically Informed Sequence Differences Among the Collaborative Cross Strains and Their Founders
por: Oreper, Daniel, et al.
Publicado: (2017)

Loci Contributing to Boric Acid Toxicity in Two Reference Populations of Drosophila melanogaster
por: Najarro, Michael A., et al.
Publicado: (2017)

The Beavis Effect in Next-Generation Mapping Panels in Drosophila melanogaster
por: King, Elizabeth G., et al.
Publicado: (2017)

Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice
por: Gralinski, Lisa E., et al.
Publicado: (2017)

Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross
por: Green, Richard, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jie03d7vh30hiqqfa1ubp9sq9m