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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies
Although our knowledge of the biology of brain tumors has increased tremendously over the past decade, progress in treatment of these deadly diseases remains modest. Developing in vivo models that faithfully mirror human diseases is essential for the validation of new therapeutic approaches. Genetic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Basel
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175043/ https://www.ncbi.nlm.nih.gov/pubmed/25008045 http://dx.doi.org/10.1007/s00018-014-1675-3 |