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IL-21 Promotes Late Activator APC-Mediated T Follicular Helper Cell Differentiation in Experimental Pulmonary Virus Infection
IL-21 is a type-I cytokine that has pleiotropic immuno-modulatory effects. Primarily produced by activated T cells including NKT and T(FH) cells, IL-21 plays a pivotal role in promoting T(FH) differentiation through poorly understood cellular and molecular mechanisms. Here, employing a mouse model o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175070/ https://www.ncbi.nlm.nih.gov/pubmed/25251568 http://dx.doi.org/10.1371/journal.pone.0105872 |