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Association Between HIV-1 Coreceptor Usage and Resistance to Broadly Neutralizing Antibodies

BACKGROUND: Recently discovered broadly neutralizing antibodies have revitalized hopes of developing a universal vaccine against HIV-1. Mainly responsible for new infections are variants only using CCR5 for cell entry, whereas CXCR4-using variants can become dominant in later infection stages. METHO...

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Detalles Bibliográficos
Autores principales: Pfeifer, Nico, Walter, Hauke, Lengauer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175123/
https://www.ncbi.nlm.nih.gov/pubmed/25072615
http://dx.doi.org/10.1097/QAI.0000000000000283