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Leydig cell tumors of the testis: a case report
BACKGROUND: Leydig cell tumors are the most common non-germ cell gonadal tumors with apparent increased incidence in the last few years. They are usually benign tumors. We report a case of Leydig cell tumor of testis in a patient presenting atypical features. CASE PRESENTATION: A 29-year-old Caucasi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175283/ https://www.ncbi.nlm.nih.gov/pubmed/25230718 http://dx.doi.org/10.1186/1756-0500-7-656 |
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author | Gheorghisan-Galateanu, Ancuta Augustina |
author_facet | Gheorghisan-Galateanu, Ancuta Augustina |
author_sort | Gheorghisan-Galateanu, Ancuta Augustina |
collection | PubMed |
description | BACKGROUND: Leydig cell tumors are the most common non-germ cell gonadal tumors with apparent increased incidence in the last few years. They are usually benign tumors. We report a case of Leydig cell tumor of testis in a patient presenting atypical features. CASE PRESENTATION: A 29-year-old Caucasian man, born with right cryptorchidism, corrected without medical treatment before the age of two years, was diagnosed with Leydig cell tumor. Two years after diagnosis was identified moderately elevated estradiol serum level, in the context of a significant overweight, hormonal changes which had maintained after unilateral orchiectomy and after the patient's return to normal weight. Four years after unilateral orchiectomy, elevated value of estradiol persisted and subdiaphragmatic micro lymphadenopathy was observed. CONCLUSIONS: Despite the favorable evolution of the patient four years after unilateral orchiectomy, long-term follow-up is necessary to exclude recurrence or metastasis to the testis. The endocrine profile and imaging investigations need to be repeated periodically. The changes in the hormonal assay and any new aspects on computed tomography scan can be used as a marker of tumor recurrence and require careful screening and the correct therapeutic decisions. |
format | Online Article Text |
id | pubmed-4175283 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41752832014-09-27 Leydig cell tumors of the testis: a case report Gheorghisan-Galateanu, Ancuta Augustina BMC Res Notes Case Report BACKGROUND: Leydig cell tumors are the most common non-germ cell gonadal tumors with apparent increased incidence in the last few years. They are usually benign tumors. We report a case of Leydig cell tumor of testis in a patient presenting atypical features. CASE PRESENTATION: A 29-year-old Caucasian man, born with right cryptorchidism, corrected without medical treatment before the age of two years, was diagnosed with Leydig cell tumor. Two years after diagnosis was identified moderately elevated estradiol serum level, in the context of a significant overweight, hormonal changes which had maintained after unilateral orchiectomy and after the patient's return to normal weight. Four years after unilateral orchiectomy, elevated value of estradiol persisted and subdiaphragmatic micro lymphadenopathy was observed. CONCLUSIONS: Despite the favorable evolution of the patient four years after unilateral orchiectomy, long-term follow-up is necessary to exclude recurrence or metastasis to the testis. The endocrine profile and imaging investigations need to be repeated periodically. The changes in the hormonal assay and any new aspects on computed tomography scan can be used as a marker of tumor recurrence and require careful screening and the correct therapeutic decisions. BioMed Central 2014-09-18 /pmc/articles/PMC4175283/ /pubmed/25230718 http://dx.doi.org/10.1186/1756-0500-7-656 Text en © Gheorghisan-Galateanu; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Gheorghisan-Galateanu, Ancuta Augustina Leydig cell tumors of the testis: a case report |
title | Leydig cell tumors of the testis: a case report |
title_full | Leydig cell tumors of the testis: a case report |
title_fullStr | Leydig cell tumors of the testis: a case report |
title_full_unstemmed | Leydig cell tumors of the testis: a case report |
title_short | Leydig cell tumors of the testis: a case report |
title_sort | leydig cell tumors of the testis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175283/ https://www.ncbi.nlm.nih.gov/pubmed/25230718 http://dx.doi.org/10.1186/1756-0500-7-656 |
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