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The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation
BACKGROUND: The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood. METHODS:...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175287/ https://www.ncbi.nlm.nih.gov/pubmed/25216995 http://dx.doi.org/10.1186/1476-4598-13-215 |