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Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the ac...

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Autores principales: Kumar, Pramod, Paulose, Rekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175377/
https://www.ncbi.nlm.nih.gov/pubmed/25295057
http://dx.doi.org/10.1155/2014/695387
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author Kumar, Pramod
Paulose, Rekha
author_facet Kumar, Pramod
Paulose, Rekha
author_sort Kumar, Pramod
collection PubMed
description Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the actual allergens which are chemical mixtures of various ingredients. Objectives. The aims of this study are to perform patch testing in suspected ACD to cosmetics and to identify the most common allergen and cosmetic product causing dermatitis. Methods. Fifty patients with suspected ACD to cosmetics were patch-tested with 38 antigens of the Indian Cosmetic Series and 12 antigens of the Indian Standard Series. Results. The majority (58%) of patients belonged to the 21–40 years age group. The presence of ACD to cosmetics was confirmed in 38 (76%) patients. Face creams (20%), hair dyes (14%), and soaps (12%) were the most commonly implicated. The most common allergens identified were gallate mix (40%), cetrimide (28%), and thiomersal (20%). Out of a total of 2531 patches applied, positive reactions were obtained in 3.75%. Conclusion. Incidence of ACD to cosmetics was greater in females. Face creams and hair dyes were the most common cosmetic products implicated. The principal allergens were gallate mix, cetrimide, and thiomersal.
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spelling pubmed-41753772014-10-07 Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics Kumar, Pramod Paulose, Rekha Dermatol Res Pract Clinical Study Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the actual allergens which are chemical mixtures of various ingredients. Objectives. The aims of this study are to perform patch testing in suspected ACD to cosmetics and to identify the most common allergen and cosmetic product causing dermatitis. Methods. Fifty patients with suspected ACD to cosmetics were patch-tested with 38 antigens of the Indian Cosmetic Series and 12 antigens of the Indian Standard Series. Results. The majority (58%) of patients belonged to the 21–40 years age group. The presence of ACD to cosmetics was confirmed in 38 (76%) patients. Face creams (20%), hair dyes (14%), and soaps (12%) were the most commonly implicated. The most common allergens identified were gallate mix (40%), cetrimide (28%), and thiomersal (20%). Out of a total of 2531 patches applied, positive reactions were obtained in 3.75%. Conclusion. Incidence of ACD to cosmetics was greater in females. Face creams and hair dyes were the most common cosmetic products implicated. The principal allergens were gallate mix, cetrimide, and thiomersal. Hindawi Publishing Corporation 2014 2014-09-09 /pmc/articles/PMC4175377/ /pubmed/25295057 http://dx.doi.org/10.1155/2014/695387 Text en Copyright © 2014 P. Kumar and R. Paulose. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Kumar, Pramod
Paulose, Rekha
Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics
title Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics
title_full Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics
title_fullStr Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics
title_full_unstemmed Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics
title_short Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics
title_sort patch testing in suspected allergic contact dermatitis to cosmetics
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175377/
https://www.ncbi.nlm.nih.gov/pubmed/25295057
http://dx.doi.org/10.1155/2014/695387
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