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Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs
Evidence in support of safety of a gene delivery procedure is essential toward gene therapy. Previous studies using the hydrodynamics-based procedure primarily focus on gene delivery efficiency or gene function analysis in mice. The current study focuses on an assessment of the safety of computer-co...
Autores principales: | Kamimura, Kenya, Kanefuji, Tsutomu, Yokoo, Takeshi, Abe, Hiroyuki, Suda, Takeshi, Kobayashi, Yuji, Zhang, Guisheng, Aoyagi, Yutaka, Liu, Dexi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175463/ https://www.ncbi.nlm.nih.gov/pubmed/25251246 http://dx.doi.org/10.1371/journal.pone.0107203 |
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