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Association between Gene Expression Profiles and Clinical Outcome of Pemetrexed-Based Treatment in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Exploratory Results from a Phase II Study

INTRODUCTION: We report exploratory gene-expression profiling data from a single-arm Phase-II-study in patients with non-squamous (ns)NSCLC treated with pemetrexed and cisplatin. Previously disclosed results indicated a significant association of low thymidylate-synthase (TS)-expression with longer...

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Detalles Bibliográficos
Autores principales:	Fennell, Dean A., Myrand, Scott P., Nguyen, Tuan S., Ferry, David, Kerr, Keith M., Maxwell, Perry, Moore, Stephen D., Visseren-Grul, Carla, Das, Mayukh, Nicolson, Marianne C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175467/ https://www.ncbi.nlm.nih.gov/pubmed/25250715 http://dx.doi.org/10.1371/journal.pone.0107455

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