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Association between Gene Expression Profiles and Clinical Outcome of Pemetrexed-Based Treatment in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Exploratory Results from a Phase II Study
INTRODUCTION: We report exploratory gene-expression profiling data from a single-arm Phase-II-study in patients with non-squamous (ns)NSCLC treated with pemetrexed and cisplatin. Previously disclosed results indicated a significant association of low thymidylate-synthase (TS)-expression with longer...
Autores principales: | Fennell, Dean A., Myrand, Scott P., Nguyen, Tuan S., Ferry, David, Kerr, Keith M., Maxwell, Perry, Moore, Stephen D., Visseren-Grul, Carla, Das, Mayukh, Nicolson, Marianne C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175467/ https://www.ncbi.nlm.nih.gov/pubmed/25250715 http://dx.doi.org/10.1371/journal.pone.0107455 |
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