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Early handling attenuates enhancement of glucocorticoid receptors in the prefrontal cortex in an animal model of post-traumatic stress disorder

BACKGROUND: Changes in glucocorticoid receptors (GRs) have been implicated in the pathogenesis of stress related psychiatric disorders such as depression and post-traumatic stress disorder (PTSD). Abnormal adaptation of the stress-response system following traumatic stress can lead to an altered hyp...

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Detalles Bibliográficos
Autores principales: George, Sophie A, Stout, Stephanie A, Tan, Melissa, Knox, Dayan, Liberzon, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175489/
https://www.ncbi.nlm.nih.gov/pubmed/24289278
http://dx.doi.org/10.1186/2045-5380-3-22