A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory

Histone deacetylases (HDACs) are a family of chromatin remodeling enzymes that restrict access of transcription factors to the DNA, thereby repressing gene expression. In contrast, histone acetyltransferases (HATs) relax the chromatin structure allowing for an active chromatin state and promoting ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahgoub, Melissa, Monteggia, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175496/
https://www.ncbi.nlm.nih.gov/pubmed/25227251
http://dx.doi.org/10.1101/lm.036012.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175496/
https://www.ncbi.nlm.nih.gov/pubmed/25227251
http://dx.doi.org/10.1101/lm.036012.114

Ejemplares similares