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A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory
Histone deacetylases (HDACs) are a family of chromatin remodeling enzymes that restrict access of transcription factors to the DNA, thereby repressing gene expression. In contrast, histone acetyltransferases (HATs) relax the chromatin structure allowing for an active chromatin state and promoting ge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175496/ https://www.ncbi.nlm.nih.gov/pubmed/25227251 http://dx.doi.org/10.1101/lm.036012.114 |