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Focal Transplantation of Human iPSC-Derived Glial-Rich Neural Progenitors Improves Lifespan of ALS Mice
Transplantation of glial-rich neural progenitors has been demonstrated to attenuate motor neuron degeneration and disease progression in rodent models of mutant superoxide dismutase 1 (SOD1)-mediated amyotrophic lateral sclerosis (ALS). However, translation of these results into a clinical setting r...
Autores principales: | Kondo, Takayuki, Funayama, Misato, Tsukita, Kayoko, Hotta, Akitsu, Yasuda, Akimasa, Nori, Satoshi, Kaneko, Shinjiro, Nakamura, Masaya, Takahashi, Ryosuke, Okano, Hideyuki, Yamanaka, Shinya, Inoue, Haruhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175543/ https://www.ncbi.nlm.nih.gov/pubmed/25254338 http://dx.doi.org/10.1016/j.stemcr.2014.05.017 |
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