Cargando…
The landscape of kinase fusions in cancer
Human cancer genomes harbour a variety of alterations leading to the deregulation of key pathways in tumour cells. The genomic characterization of tumours has uncovered numerous genes recurrently mutated, deleted or amplified, but gene fusions have not been characterized as extensively. Here we deve...
Autores principales: | Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175590/ https://www.ncbi.nlm.nih.gov/pubmed/25204415 http://dx.doi.org/10.1038/ncomms5846 |
Ejemplares similares
-
Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes
por: Jones, Siân, et al.
Publicado: (2014) -
Landscape of potentially targetable receptor tyrosine kinase fusions in diverse cancers by DNA-based profiling
por: Wang, Tiantian, et al.
Publicado: (2022) -
The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA
por: Lee, Jessica K., et al.
Publicado: (2022) -
Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods
por: Haas, Brian J., et al.
Publicado: (2019) -
Tecnología Push en Internet /
por: Cerami, Ethan
Publicado: (1999)