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The landscape of kinase fusions in cancer

Human cancer genomes harbour a variety of alterations leading to the deregulation of key pathways in tumour cells. The genomic characterization of tumours has uncovered numerous genes recurrently mutated, deleted or amplified, but gene fusions have not been characterized as extensively. Here we deve...

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Detalles Bibliográficos
Autores principales: Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175590/
https://www.ncbi.nlm.nih.gov/pubmed/25204415
http://dx.doi.org/10.1038/ncomms5846

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