Cargando…

Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer

INTRODUCTION: This study compared four different volumetric modulated arc therapy (VMAT) beam arrangements for the treatment of early-stage prostate cancer examining plan quality and the impact on a radiotherapy department's resources. METHODS: Twenty prostate cases were retrospectively planned...

Descripción completa

Detalles Bibliográficos
Autores principales: Elith, Craig A, Dempsey, Shane E, Warren-Forward, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175844/
https://www.ncbi.nlm.nih.gov/pubmed/26229643
http://dx.doi.org/10.1002/jmrs.52
_version_ 1782336540338290688
author Elith, Craig A
Dempsey, Shane E
Warren-Forward, Helen M
author_facet Elith, Craig A
Dempsey, Shane E
Warren-Forward, Helen M
author_sort Elith, Craig A
collection PubMed
description INTRODUCTION: This study compared four different volumetric modulated arc therapy (VMAT) beam arrangements for the treatment of early-stage prostate cancer examining plan quality and the impact on a radiotherapy department's resources. METHODS: Twenty prostate cases were retrospectively planned using four VMAT beam arrangements (1) a partial arc (PA), (2) one arc (1A), (3) one arc plus a partial arc (1A + PA) and (4) two arcs (2A). The quality of the dose distributions generated were compared by examining the overall plan quality, the homogeneity and conformity to the planning target volume (PTV), the number of monitor units and the dose delivered to the organs at risk. Departmental resources were considered by recording the planning time and beam delivery time. RESULTS: Each technique produced a plan of similar quality that was considered adequate for treatment; though some differences were noted. The 1A, 1A + PA and 2A plans demonstrated a better conformity to the PTV which correlated to improved sparing of the rectum in the 60–70 Gy range for the 1A + PA and 2A techniques. The time needed to generate the plans was different for each technique ranging from 13.1 min for 1A + PA to 17.8 min for 1A. The PA beam delivery time was fastest with a mean time of 0.9 min. Beam-on times then increased with an increase in the number of arcs up to an average of 2.2 min for the 2A technique. CONCLUSION: Which VMAT technique is best suited for clinical implementation for the treatment of prostate cancer may be dictated by the individual patient and the availability of departmental resources.
format Online
Article
Text
id pubmed-4175844
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BlackWell Publishing Ltd
record_format MEDLINE/PubMed
spelling pubmed-41758442014-09-30 Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer Elith, Craig A Dempsey, Shane E Warren-Forward, Helen M J Med Radiat Sci Original Articles INTRODUCTION: This study compared four different volumetric modulated arc therapy (VMAT) beam arrangements for the treatment of early-stage prostate cancer examining plan quality and the impact on a radiotherapy department's resources. METHODS: Twenty prostate cases were retrospectively planned using four VMAT beam arrangements (1) a partial arc (PA), (2) one arc (1A), (3) one arc plus a partial arc (1A + PA) and (4) two arcs (2A). The quality of the dose distributions generated were compared by examining the overall plan quality, the homogeneity and conformity to the planning target volume (PTV), the number of monitor units and the dose delivered to the organs at risk. Departmental resources were considered by recording the planning time and beam delivery time. RESULTS: Each technique produced a plan of similar quality that was considered adequate for treatment; though some differences were noted. The 1A, 1A + PA and 2A plans demonstrated a better conformity to the PTV which correlated to improved sparing of the rectum in the 60–70 Gy range for the 1A + PA and 2A techniques. The time needed to generate the plans was different for each technique ranging from 13.1 min for 1A + PA to 17.8 min for 1A. The PA beam delivery time was fastest with a mean time of 0.9 min. Beam-on times then increased with an increase in the number of arcs up to an average of 2.2 min for the 2A technique. CONCLUSION: Which VMAT technique is best suited for clinical implementation for the treatment of prostate cancer may be dictated by the individual patient and the availability of departmental resources. BlackWell Publishing Ltd 2014-06 2014-05-20 /pmc/articles/PMC4175844/ /pubmed/26229643 http://dx.doi.org/10.1002/jmrs.52 Text en © 2014 The Authors. Journal of Medical Radiation Sciences published by Wiley Publishing Asia Pty Ltd on behalf of Australian Institute of Radiography and New Zealand Institute of Medical Radiation Technology. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Elith, Craig A
Dempsey, Shane E
Warren-Forward, Helen M
Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
title Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
title_full Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
title_fullStr Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
title_full_unstemmed Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
title_short Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
title_sort comparing four volumetric modulated arc therapy beam arrangements for the treatment of early-stage prostate cancer
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175844/
https://www.ncbi.nlm.nih.gov/pubmed/26229643
http://dx.doi.org/10.1002/jmrs.52
work_keys_str_mv AT elithcraiga comparingfourvolumetricmodulatedarctherapybeamarrangementsforthetreatmentofearlystageprostatecancer
AT dempseyshanee comparingfourvolumetricmodulatedarctherapybeamarrangementsforthetreatmentofearlystageprostatecancer
AT warrenforwardhelenm comparingfourvolumetricmodulatedarctherapybeamarrangementsforthetreatmentofearlystageprostatecancer