Cargando…

Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs

OBJECTIVE: 1,3,4-oxadiazole ring is a versatile moiety with a wide range of pharmacological properties. The present work deals with the synthesis and evaluation of the anti-inflammatory activity of two novel 2,5-disubstituted-1,3,4-oxadiazoles (OSD and OPD). MATERIALS AND METHODS: Carrageenan-induce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Durgashivaprasad, Ega, Mathew, Geetha, Sebastian, Sarine, Reddy, S.A Manohar, Mudgal, Jayesh, Nampurath, Gopalan Kutty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175889/ https://www.ncbi.nlm.nih.gov/pubmed/25298582 http://dx.doi.org/10.4103/0253-7613.140584

Ejemplares similares

Synthesis, Antimicrobial and Antiinflammatory Activity of 2,5-Disubstituted-1,3,4-oxadiazoles
por: Nagalakshmi, G.
Publicado: (2008)

Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives
por: Jafari, Elham, et al.
Publicado: (2017)

Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives
por: Rana, Sibghat Mansoor, et al.
Publicado: (2023)

Synthesis, Characterization, and In Vitro Anticancer Evaluation of Novel 2,5-Disubstituted 1,3,4-Oxadiazole Analogue
por: Salahuddin,, et al.
Publicado: (2014)

Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats
por: John, Jessy, et al.
Publicado: (2015)

Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats
por: Nampoothiri, Madhavan, et al.
Publicado: (2015)

Catalyst-Free Visible-Light-Promoted Cyclization of Aldehydes: Access to 2,5-Disubstituted 1,3,4-Oxadiazole Derivatives
por: Li, Jian, et al.
Publicado: (2021)

Synthesis, characterization, antimicrobial, and pharmacological evaluation of some 2, 5-disubstituted sulfonyl amino 1,3,4-oxadiazole and 2-amino-disubstituted 1,3,4-thiadiazole derivatives
por: Pal, Dilipkumar, et al.
Publicado: (2014)

A One-Pot Synthesis-Functionalization Strategy for Streamlined Access to 2,5-Disubstituted 1,3,4-Oxadiazoles from Carboxylic Acids
por: Matheau-Raven, Daniel, et al.
Publicado: (2022)

Copper-Catalyzed One-Pot Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from Arylacetic Acids and Hydrazides via Dual Oxidation
por: Lekkala, Chinnari, et al.
Publicado: (2022)

Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents
por: Rezki, Nadjet, et al.
Publicado: (2015)

Synthesis, spectral characterization, and biological studies of 3,5-disubstituted-1,3,4-oxadiazole-2(3H)-thione derivatives
por: ÖZYAZICI, Tuğçe, et al.
Publicado: (2021)

Synthesis of 2,5-Dialkyl-1,3,4-oxadiazoles Bearing Carboxymethylamino Groups
por: Łuczyński, Marcin, et al.
Publicado: (2022)

Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole
por: Glomb, Teresa, et al.
Publicado: (2018)

2,5-Bis(5-methylpyrazin-2-yl)-1,3,4-oxadiazole
por: Ju, Yue, et al.
Publicado: (2011)

2,5-Bis(4-methoxyphenyl)-1,3,4-oxadiazole
por: Fun, Hoong-Kun, et al.
Publicado: (2010)

Novel 3-Acetyl-2,5-disubstituted-1,3,4-oxadiazolines: Synthesis and Biological Activity
por: Paruch, Kinga, et al.
Publicado: (2020)

In vivo Evaluation of Two Thiazolidin-4-one Derivatives in High Sucrose Diet Fed Pre-diabetic Mice and Their Modulatory Effect on AMPK, Akt and p38 MAP Kinase in L6 Cells
por: Mudgal, Jayesh, et al.
Publicado: (2016)

Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives
por: Glomb, Teresa, et al.
Publicado: (2021)

Design and Microwave-assisted Synthesis of 1,3,4-Oxadiazole Derivatives for Analgesic and Anti-inflammatory Activity
por: Biju, CR, et al.
Publicado: (2012)

New 1,3,4-Oxadiazole Derivatives of Pyridothiazine-1,1-Dioxide with Anti-Inflammatory Activity
por: Glomb, Teresa, et al.
Publicado: (2020)

2,5-Bis[2-(2-methoxyethoxy)phenyl]-1,3,4-oxadiazole
por: Tian, Xia, et al.
Publicado: (2009)

Synthesis, characterization and biological evaluation of novel 2,5 substituted-1,3,4 oxadiazole derivatives
por: Kavitha, Selvaraj, et al.
Publicado: (2017)

Biological Activity, Lipophilicity and Cytotoxicity of Novel 3-Acetyl-2,5-disubstituted-1,3,4-oxadiazolines
por: Paruch, Kinga, et al.
Publicado: (2021)

5-Phenyl-1,3,4-oxadiazol-2-amine
por: Song, Man-Man, et al.
Publicado: (2012)

1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction
por: Wang, Qian, et al.
Publicado: (2019)

4,4′-(1,3,4-Oxadiazole-2,5-diyl)dipyridinium dibromide monohydrate
por: Han, Meng Ting, et al.
Publicado: (2010)

Synthesis, Characterization, and Preclinical Evaluation of New Thiazolidin-4-Ones Substituted with p-Chlorophenoxy Acetic Acid and Clofibric Acid against Insulin Resistance and Metabolic Disorder
por: Gowdra, Vasantharaju S., et al.
Publicado: (2014)

Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
por: Aksenov, Alexander V., et al.
Publicado: (2019)

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
por: Stecoza, Camelia Elena, et al.
Publicado: (2021)

Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells
por: Nampoothiri, Madhavan, et al.
Publicado: (2014)

Synthesis, analgesic and anti-inflammatory activities of new methyl-imidazolyl-1,3,4-oxadiazoles and 1,2,4-triazoles
por: Almasirad, Ali, et al.
Publicado: (2014)

2-[3,4-Dibutoxy-5-(5-phenyl-1,3,4-oxadiazol-2-yl)-2-thienyl]-5-phenyl-1,3,4-oxadiazole
por: Li, Hai-lin, et al.
Publicado: (2008)

catena-Poly[[dianilinedichloridocopper(II)]-μ(2)-2,5-bis(4-pyridyl)-1,3,4-oxadiazole]
por: Meng, Qinglong, et al.
Publicado: (2009)

Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review
por: Wang, Jing-Jing, et al.
Publicado: (2022)

1,3,4-Oxadiazole N-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities
por: Al-Wahaibi, Lamya H., et al.
Publicado: (2021)

Structure–Activity Relationships and Antiplasmodial Potencies of Novel 3,4-Disubstituted 1,2,5-Oxadiazoles
por: Hochegger, Patrick, et al.
Publicado: (2023)

Synthesis and fungicidal activity of novel 2,5-disubstituted-1,3,4- thiadiazole derivatives containing 5-phenyl-2-furan
por: Cui, Zi-Ning, et al.
Publicado: (2016)

2-Phenyl-5-(p-tolyl)-1,3,4-oxadiazole
por: Cordes, David B., et al.
Publicado: (2011)

Synthesis, Characterization and Biological Activity Studies of 1,3,4-Oxadiazole Analogs
por: Bhat, KI, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_rgcp4ioes2kj9vl0p4jk805mbq