A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin

Medication errors may occur at any point during patient care in the health care system. Drug interaction in known with macrolide antibiotics and ranolazine and is primarily related to effects on the cytochrome P4503A (CYP3A) metabolic pathway. This case highlights medication errors that resulted in...

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Detalles Bibliográficos
Autores principales: Mishra, Ajay, Pandya, Himanshu V., Dave, Nikhil, Mathew, Mahesh, Sapre, Chinmaye M., Chaudhary, Sneha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175894/
https://www.ncbi.nlm.nih.gov/pubmed/25298587
http://dx.doi.org/10.4103/0253-7613.140593
Descripción
Sumario:Medication errors may occur at any point during patient care in the health care system. Drug interaction in known with macrolide antibiotics and ranolazine and is primarily related to effects on the cytochrome P4503A (CYP3A) metabolic pathway. This case highlights medication errors that resulted in rare debilitating neurological adverse effects of ranolazine in an elderly due to drug interaction with clarithromycin.

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