A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin

Medication errors may occur at any point during patient care in the health care system. Drug interaction in known with macrolide antibiotics and ranolazine and is primarily related to effects on the cytochrome P4503A (CYP3A) metabolic pathway. This case highlights medication errors that resulted in...

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Autores principales: Mishra, Ajay, Pandya, Himanshu V., Dave, Nikhil, Mathew, Mahesh, Sapre, Chinmaye M., Chaudhary, Sneha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175894/
https://www.ncbi.nlm.nih.gov/pubmed/25298587
http://dx.doi.org/10.4103/0253-7613.140593
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author Mishra, Ajay
Pandya, Himanshu V.
Dave, Nikhil
Mathew, Mahesh
Sapre, Chinmaye M.
Chaudhary, Sneha
author_facet Mishra, Ajay
Pandya, Himanshu V.
Dave, Nikhil
Mathew, Mahesh
Sapre, Chinmaye M.
Chaudhary, Sneha
author_sort Mishra, Ajay
collection PubMed
description Medication errors may occur at any point during patient care in the health care system. Drug interaction in known with macrolide antibiotics and ranolazine and is primarily related to effects on the cytochrome P4503A (CYP3A) metabolic pathway. This case highlights medication errors that resulted in rare debilitating neurological adverse effects of ranolazine in an elderly due to drug interaction with clarithromycin.
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spelling pubmed-41758942014-10-08 A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin Mishra, Ajay Pandya, Himanshu V. Dave, Nikhil Mathew, Mahesh Sapre, Chinmaye M. Chaudhary, Sneha Indian J Pharmacol Drug Watch Medication errors may occur at any point during patient care in the health care system. Drug interaction in known with macrolide antibiotics and ranolazine and is primarily related to effects on the cytochrome P4503A (CYP3A) metabolic pathway. This case highlights medication errors that resulted in rare debilitating neurological adverse effects of ranolazine in an elderly due to drug interaction with clarithromycin. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4175894/ /pubmed/25298587 http://dx.doi.org/10.4103/0253-7613.140593 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Mishra, Ajay
Pandya, Himanshu V.
Dave, Nikhil
Mathew, Mahesh
Sapre, Chinmaye M.
Chaudhary, Sneha
A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
title A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
title_full A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
title_fullStr A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
title_full_unstemmed A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
title_short A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
title_sort rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175894/
https://www.ncbi.nlm.nih.gov/pubmed/25298587
http://dx.doi.org/10.4103/0253-7613.140593
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