Factor XI deficiency diagnosed following use of adalimumab

Adalimumab is a drug used in the treatment of refractory psoriasis. We present a case of a 55-year-old male patient who developed petechiae and purpura after the ninth dose of adalimumab therapy. The results of laboratory investigations revealed factor XI (F.XI) deficiency. It should be recognized t...

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Autores principales: Cetin, Guven, Karatoprak, Cumali, Kiskac, Muharrem, Zorlu, Mehmet, Rezvani, Aylin, Cikrikcioglu, Mehmet Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175897/
https://www.ncbi.nlm.nih.gov/pubmed/25298590
http://dx.doi.org/10.4103/0253-7613.140596
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author Cetin, Guven
Karatoprak, Cumali
Kiskac, Muharrem
Zorlu, Mehmet
Rezvani, Aylin
Cikrikcioglu, Mehmet Ali
author_facet Cetin, Guven
Karatoprak, Cumali
Kiskac, Muharrem
Zorlu, Mehmet
Rezvani, Aylin
Cikrikcioglu, Mehmet Ali
author_sort Cetin, Guven
collection PubMed
description Adalimumab is a drug used in the treatment of refractory psoriasis. We present a case of a 55-year-old male patient who developed petechiae and purpura after the ninth dose of adalimumab therapy. The results of laboratory investigations revealed factor XI (F.XI) deficiency. It should be recognized that F XI deficiency may develop in patients using long-term adalimumab, leading to increased risk of bleeding.
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spelling pubmed-41758972014-10-08 Factor XI deficiency diagnosed following use of adalimumab Cetin, Guven Karatoprak, Cumali Kiskac, Muharrem Zorlu, Mehmet Rezvani, Aylin Cikrikcioglu, Mehmet Ali Indian J Pharmacol Drug Watch Adalimumab is a drug used in the treatment of refractory psoriasis. We present a case of a 55-year-old male patient who developed petechiae and purpura after the ninth dose of adalimumab therapy. The results of laboratory investigations revealed factor XI (F.XI) deficiency. It should be recognized that F XI deficiency may develop in patients using long-term adalimumab, leading to increased risk of bleeding. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4175897/ /pubmed/25298590 http://dx.doi.org/10.4103/0253-7613.140596 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Cetin, Guven
Karatoprak, Cumali
Kiskac, Muharrem
Zorlu, Mehmet
Rezvani, Aylin
Cikrikcioglu, Mehmet Ali
Factor XI deficiency diagnosed following use of adalimumab
title Factor XI deficiency diagnosed following use of adalimumab
title_full Factor XI deficiency diagnosed following use of adalimumab
title_fullStr Factor XI deficiency diagnosed following use of adalimumab
title_full_unstemmed Factor XI deficiency diagnosed following use of adalimumab
title_short Factor XI deficiency diagnosed following use of adalimumab
title_sort factor xi deficiency diagnosed following use of adalimumab
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175897/
https://www.ncbi.nlm.nih.gov/pubmed/25298590
http://dx.doi.org/10.4103/0253-7613.140596
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