Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma

Thalidomide developed in 1954 for morning sickness had proven to be a teratogen and hence was withdrawn from market. Resurgence of thalidomide began as an immunomodulator when it was shown to be effective in the management of multiple myeloma and many conditions like erythema nodosum leprosum, graft...

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Autores principales: Das, Anupam, Sil, Amrita, Mishra, Vivek, Das, Nilay Kanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175899/
https://www.ncbi.nlm.nih.gov/pubmed/25298592
http://dx.doi.org/10.4103/0253-7613.140598
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author Das, Anupam
Sil, Amrita
Mishra, Vivek
Das, Nilay Kanti
author_facet Das, Anupam
Sil, Amrita
Mishra, Vivek
Das, Nilay Kanti
author_sort Das, Anupam
collection PubMed
description Thalidomide developed in 1954 for morning sickness had proven to be a teratogen and hence was withdrawn from market. Resurgence of thalidomide began as an immunomodulator when it was shown to be effective in the management of multiple myeloma and many conditions like erythema nodosum leprosum, graft versus host disease, recurrent aphthous ulcers etc. We report a case of Stevens Johnson syndrome-toxic epidermal necrolysis developing in an elderly male who was prescribed thalidomide after being diagnosed with multiple myeloma.
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spelling pubmed-41758992014-10-08 Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma Das, Anupam Sil, Amrita Mishra, Vivek Das, Nilay Kanti Indian J Pharmacol Drug Watch Thalidomide developed in 1954 for morning sickness had proven to be a teratogen and hence was withdrawn from market. Resurgence of thalidomide began as an immunomodulator when it was shown to be effective in the management of multiple myeloma and many conditions like erythema nodosum leprosum, graft versus host disease, recurrent aphthous ulcers etc. We report a case of Stevens Johnson syndrome-toxic epidermal necrolysis developing in an elderly male who was prescribed thalidomide after being diagnosed with multiple myeloma. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4175899/ /pubmed/25298592 http://dx.doi.org/10.4103/0253-7613.140598 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Das, Anupam
Sil, Amrita
Mishra, Vivek
Das, Nilay Kanti
Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
title Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
title_full Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
title_fullStr Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
title_full_unstemmed Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
title_short Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
title_sort steven's johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175899/
https://www.ncbi.nlm.nih.gov/pubmed/25298592
http://dx.doi.org/10.4103/0253-7613.140598
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