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Domain ChIRP reveals the modularity of long noncoding RNA architecture, chromatin interactions, and function

Little is known about the functional domain architecture of long RNA molecules, mainly because of a relative paucity of suitable methods to analyze RNA function at a domain level. Here we describe domain-specific chromatin isolation by RNA purification (dChIRP), a scalable technique to dissect pairw...

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Detalles Bibliográficos
Autores principales: Quinn, Jeffrey J, Ilik, Ibrahim A, Qu, Kun, Georgiev, Plamen, Chu, Ci, Akhtar, Asifa, Chang, Howard Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175979/
https://www.ncbi.nlm.nih.gov/pubmed/24997788
http://dx.doi.org/10.1038/nbt.2943