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PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway
BACKGROUND: PIN2/TRF1-interacting telomerase inhibitor1 (PinX1) was recently suggested as a putative tumor suppressor in several types of human cancer, based on its binding to and inhibition of telomerase. Moreover, loss of PinX1 has been detected in many human malignancies. However, the possible in...
Autores principales: | Liu, Jian-Ye, Qian, Dong, He, Li-Ru, Li, Yong-Hong, Liao, Yi-Ji, Mai, Shi-Juan, Tian, Xiao-Peng, Liu, Yan-Hui, Zhang, Jia-Xing, Kung, Hsiang-Fu, Zeng, Yi-Xin, Zhou, Fang-Jian, Xie, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176126/ https://www.ncbi.nlm.nih.gov/pubmed/24268029 http://dx.doi.org/10.1186/1476-4598-12-148 |
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