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Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer

Plau codes for the urokinase-type plasminogen activator (uPA), critical in cancer metastasis. While the mechanisms driving its overexpression in tumorigenic processes are unknown, it is regulated by the AP-1 transcriptional complex in diverse situations. The AP-1 component Fra-1 being overexpressed...

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Detalles Bibliográficos
Autores principales:	Moquet-Torcy, Gabriel, Tolza, Claire, Piechaczyk, Marc, Jariel-Encontre, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176185/ https://www.ncbi.nlm.nih.gov/pubmed/25200076 http://dx.doi.org/10.1093/nar/gku814

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