Direct binding of the Alu binding protein dimer SRP9/14 to 40S ribosomal subunits promotes stress granule formation and is regulated by Alu RNA

Stress granules (SGs) are formed in response to stress, contain mRNAs, 40S ribosomal subunits, initiation factors, RNA-binding and signaling proteins, and promote cell survival. Our study describes a novel function of the protein heterodimer SRP9/14 and Alu RNA in SG formation and disassembly. In hu...

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Detalles Bibliográficos
Autores principales: Berger, A., Ivanova, E., Gareau, C., Scherrer, A., Mazroui, R., Strub, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176187/
https://www.ncbi.nlm.nih.gov/pubmed/25200073
http://dx.doi.org/10.1093/nar/gku822

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