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Discovery of Novel-Scaffold Monoamine Transporter Ligands via in Silico Screening with the S1 Pocket of the Serotonin Transporter

[Image: see text] Discovery of new inhibitors of the plasmalemmal monoamine transporters (MATs) continues to provide pharmacotherapeutic options for depression, addiction, attention deficit disorders, psychosis, narcolepsy, and Parkinson’s disease. The windfall of high-resolution MAT structural info...

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Detalles Bibliográficos
Autores principales: Nolan, Tammy L., Geffert, Laura M., Kolber, Benedict J., Madura, Jeffry D., Surratt, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176318/
https://www.ncbi.nlm.nih.gov/pubmed/25003748
http://dx.doi.org/10.1021/cn500133b