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A high security double lock and key mechanism in HUH relaxases controls oriT-processing for plasmid conjugation

Relaxases act as DNA selection sieves in conjugative plasmid transfer. Most plasmid relaxases belong to the HUH endonuclease family. TrwC, the relaxase of plasmid R388, is the prototype of the HUH relaxase family, which also includes TraI of plasmid F. In this article we demonstrate that TrwC proces...

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Detalles Bibliográficos
Autores principales:	Carballeira, José Daniel, González-Pérez, Blanca, Moncalián, Gabriel, de la Cruz, Fernando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176350/ https://www.ncbi.nlm.nih.gov/pubmed/25123661 http://dx.doi.org/10.1093/nar/gku741

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