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Effects of supercoiling on enhancer–promoter contacts

Using Brownian dynamics simulations, we investigate here one of possible roles of supercoiling within topological domains constituting interphase chromosomes of higher eukaryotes. We analysed how supercoiling affects the interaction between enhancers and promoters that are located in the same or in...

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Detalles Bibliográficos
Autores principales:	Benedetti, Fabrizio, Dorier, Julien, Stasiak, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176356/ https://www.ncbi.nlm.nih.gov/pubmed/25123662 http://dx.doi.org/10.1093/nar/gku759

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