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Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence
Barcoded vectors are promising tools for investigating clonal diversity and dynamics in hematopoietic gene therapy. Analysis of clones marked with barcoded vectors requires accurate identification of potentially large numbers of individually rare barcodes, when the exact number, sequence identity an...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176369/ https://www.ncbi.nlm.nih.gov/pubmed/25013183 http://dx.doi.org/10.1093/nar/gku607 |