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Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes

Modified mRNA cap analogs aid in the study of mRNA-related processes and may enable creation of novel therapeutic interventions. We report the synthesis and properties of 11 dinucleotide cap analogs bearing a single boranophosphate modification at either the α-, β- or γ-position of the 5′,5′-triphos...

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Detalles Bibliográficos
Autores principales:	Kowalska, Joanna, Wypijewska del Nogal, Anna, Darzynkiewicz, Zbigniew M., Buck, Janina, Nicola, Corina, Kuhn, Andreas N., Lukaszewicz, Maciej, Zuberek, Joanna, Strenkowska, Malwina, Ziemniak, Marcin, Maciejczyk, Maciej, Bojarska, Elzbieta, Rhoads, Robert E., Darzynkiewicz, Edward, Sahin, Ugur, Jemielity, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176373/ https://www.ncbi.nlm.nih.gov/pubmed/25150148 http://dx.doi.org/10.1093/nar/gku757

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