A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL

Regulation of transcription is fundamental to development and physiology, and occurs through binding of transcription factors to specific DNA sequences in the genome. CSL (CBF1/Suppressor of Hairless/LAG-1), a core component of the Notch signaling pathway, is one such transcription factor that acts...

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Detalles Bibliográficos
Autores principales: Torella, Rubben, Li, Jinghua, Kinrade, Eddie, Cerda-Moya, Gustavo, Contreras, Ashley N., Foy, Robert, Stojnic, Robert, Glen, Robert C., Kovall, Rhett A., Adryan, Boris, Bray, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176381/
https://www.ncbi.nlm.nih.gov/pubmed/25114055
http://dx.doi.org/10.1093/nar/gku730

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