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Tethered Protein Display Identifies a Novel Kir3.2 (GIRK2) Regulator from Protein Scaffold Libraries
[Image: see text] Use of randomized peptide libraries to evolve molecules with new functions provides a means for developing novel regulators of protein activity. Despite the demonstrated power of such approaches for soluble targets, application of this strategy to membrane systems, such as ion chan...
Autores principales: | Bagriantsev, Sviatoslav N., Chatelain, Franck C., Clark, Kimberly A., Alagem, Noga, Reuveny, Eitan, Minor, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176385/ https://www.ncbi.nlm.nih.gov/pubmed/25028803 http://dx.doi.org/10.1021/cn5000698 |
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