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Tethered Protein Display Identifies a Novel Kir3.2 (GIRK2) Regulator from Protein Scaffold Libraries

[Image: see text] Use of randomized peptide libraries to evolve molecules with new functions provides a means for developing novel regulators of protein activity. Despite the demonstrated power of such approaches for soluble targets, application of this strategy to membrane systems, such as ion chan...

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Detalles Bibliográficos
Autores principales: Bagriantsev, Sviatoslav N., Chatelain, Franck C., Clark, Kimberly A., Alagem, Noga, Reuveny, Eitan, Minor, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176385/
https://www.ncbi.nlm.nih.gov/pubmed/25028803
http://dx.doi.org/10.1021/cn5000698

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