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Development of a Fluorescence Assay for the Characterization of Brevenal Binding to Rat Brain Synaptosomes
[Image: see text] The marine dinoflagellate Karenia brevis produces a family of neurotoxins known as brevetoxins. Brevetoxins elicit their effects by binding to and activating voltage-sensitive sodium channels (VSSCs) in cell membranes. K. brevis also produces brevenal, a brevetoxin antagonist, whic...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society and American
Society of Pharmacognosy
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176390/ https://www.ncbi.nlm.nih.gov/pubmed/25226846 http://dx.doi.org/10.1021/np500118p |