An Iridoid Glucoside and the Related Aglycones from Cornus florida

[Image: see text] A new iridoid glucoside, cornusoside A (1), and four new natural product iridoid aglycones, cornolactones A–D (2–5), together with 10 known compounds were isolated from the leaves of Cornus florida. The structures of compounds 1–5 were established by interpretation of their spectro...

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Autores principales: He, Yangqing, Peng, Jiangnan, Hamann, Mark T., West, Lyndon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176392/
https://www.ncbi.nlm.nih.gov/pubmed/25141901
http://dx.doi.org/10.1021/np5002362
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author He, Yangqing
Peng, Jiangnan
Hamann, Mark T.
West, Lyndon M.
author_facet He, Yangqing
Peng, Jiangnan
Hamann, Mark T.
West, Lyndon M.
author_sort He, Yangqing
collection PubMed
description [Image: see text] A new iridoid glucoside, cornusoside A (1), and four new natural product iridoid aglycones, cornolactones A–D (2–5), together with 10 known compounds were isolated from the leaves of Cornus florida. The structures of compounds 1–5 were established by interpretation of their spectroscopic data. Cornolactone B (3) is the first natural cis-fused tricyclic dilactone iridoid containing both a five- and a six-membered lactone ring. A biosynthesis pathway is proposed for cornolactones C (4) and D (5), the C-6 epimers of compounds 1–3.
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spelling pubmed-41763922015-08-21 An Iridoid Glucoside and the Related Aglycones from Cornus florida He, Yangqing Peng, Jiangnan Hamann, Mark T. West, Lyndon M. J Nat Prod [Image: see text] A new iridoid glucoside, cornusoside A (1), and four new natural product iridoid aglycones, cornolactones A–D (2–5), together with 10 known compounds were isolated from the leaves of Cornus florida. The structures of compounds 1–5 were established by interpretation of their spectroscopic data. Cornolactone B (3) is the first natural cis-fused tricyclic dilactone iridoid containing both a five- and a six-membered lactone ring. A biosynthesis pathway is proposed for cornolactones C (4) and D (5), the C-6 epimers of compounds 1–3. American Chemical Society and American Society of Pharmacognosy 2014-08-21 2014-09-26 /pmc/articles/PMC4176392/ /pubmed/25141901 http://dx.doi.org/10.1021/np5002362 Text en Copyright © 2014 American Chemical Society and American Society of Pharmacognosy Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle He, Yangqing
Peng, Jiangnan
Hamann, Mark T.
West, Lyndon M.
An Iridoid Glucoside and the Related Aglycones from Cornus florida
title An Iridoid Glucoside and the Related Aglycones from Cornus florida
title_full An Iridoid Glucoside and the Related Aglycones from Cornus florida
title_fullStr An Iridoid Glucoside and the Related Aglycones from Cornus florida
title_full_unstemmed An Iridoid Glucoside and the Related Aglycones from Cornus florida
title_short An Iridoid Glucoside and the Related Aglycones from Cornus florida
title_sort iridoid glucoside and the related aglycones from cornus florida
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176392/
https://www.ncbi.nlm.nih.gov/pubmed/25141901
http://dx.doi.org/10.1021/np5002362
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