Cargando…
L,L-diaminopimelate aminotransferase (DapL): a putative target for the development of narrow-spectrum antibacterial compounds
Despite the urgent need for sustained development of novel antibacterial compounds to combat the drastic rise in antibiotic resistant and emerging bacterial infections, only a few clinically relevant antibacterial drugs have been recently developed. One of the bottlenecks impeding the development of...
Autores principales: | Triassi, Alexander J., Wheatley, Matthew S., Savka, Michael A., Gan, Han Ming, Dobson, Renwick C. J., Hudson, André O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176475/ https://www.ncbi.nlm.nih.gov/pubmed/25309529 http://dx.doi.org/10.3389/fmicb.2014.00509 |
Ejemplares similares
-
Comparative Molecular Dynamics Simulations Provide Insight Into Antibiotic Interactions: A Case Study Using the Enzyme L,L-Diaminopimelate Aminotransferase (DapL)
por: Adams, Lily E., et al.
Publicado: (2020) -
L,L-Diaminopimelate
Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide
Development
por: Dobson, Renwick C. J., et al.
Publicado: (2011) -
Genomic and Biochemical Analysis of the Diaminopimelate and Lysine Biosynthesis Pathway in Verrucomicrobium spinosum: Identification and Partial Characterization of L,L-Diaminopimelate Aminotransferase and UDP-N-Acetylmuramoylalanyl-D-glutamyl-2,6-meso-Diaminopimelate Ligase
por: Nachar, Victoria R., et al.
Publicado: (2012) -
An L,L-diaminopimelate aminotransferase mutation leads to metabolic shifts and growth inhibition in Arabidopsis
por: Cavalcanti, João Henrique F, et al.
Publicado: (2018) -
Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target
por: Heath, Tahirah K., et al.
Publicado: (2018)