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The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells

Epidermal growth factor receptor (EGFR) interacting with Stat3 is considered to be an attractive therapeutic target. In the current study, we investigated the effect of resveratrol and its two 4′-methylthio-trans-stilbene derivatives (3-M-4′-MTS; S2) (3,5-DM-4″-MTS; S5) on EGFR and Stat3 activation...

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Detalles Bibliográficos
Autores principales: Cichocki, Michal, Szaefer, Hanna, Krajka-Kuźniak, Violetta, Baer-Dubowska, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176574/
https://www.ncbi.nlm.nih.gov/pubmed/25063218
http://dx.doi.org/10.1007/s11010-014-2157-5

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