Deletion of the gene encoding the reductase component of 3-ketosteroid 9α-hydroxylase in Rhodococcus equi USA-18 disrupts sterol catabolism, leading to the accumulation of 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid and 1,4-androstadiene-3,17-dione

The gene encoding the putative reductase component (KshB) of 3-ketosteroid 9α-hydroxylase was cloned from Rhodococcus equi USA-18, a cholesterol oxidase-producing strain formerly named Arthrobacter simplex USA-18, by PCR according to consensus amino acid motifs of several bacterial KshB subunits. De...

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Detalles Bibliográficos
Autores principales: Yeh, Chin-Hsing, Kuo, Yung-Shun, Chang, Che-Ming, Liu, Wen-Hsiung, Sheu, Meei-Ling, Meng, Menghsiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176589/
https://www.ncbi.nlm.nih.gov/pubmed/25201011
http://dx.doi.org/10.1186/s12934-014-0130-3

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