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Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase
BACKGROUND: Dihydroneopterin aldolase (DHNA) catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and also the epimerization of DHNP to 7,8-dihydromonapterin. Previously, we determined the crystal structure of Staphylococcus aureus DHNA (SaDHNA) in complex with the s...
Autores principales: | Blaszczyk, Jaroslaw, Lu, Zhenwei, Li, Yue, Yan, Honggao, Ji, Xinhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176595/ https://www.ncbi.nlm.nih.gov/pubmed/25264482 http://dx.doi.org/10.1186/2045-3701-4-52 |
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