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Polymersome magneto-valves for reversible capture and release of nanoparticles
Stomatocytes are polymersomes with an infolded bowl-shaped architecture. This internal cavity is connected to the outside environment via a small ‘mouth’ region. Stomatocytes are assembled from diamagnetic amphiphilic block-copolymers with a highly anisotropic magnetic susceptibility, which permits...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176683/ https://www.ncbi.nlm.nih.gov/pubmed/25248402 http://dx.doi.org/10.1038/ncomms6010 |
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author | van Rhee, P.G. Rikken, R.S.M. Abdelmohsen, L.K.E.A. Maan, J.C. Nolte, R.J.M. van Hest, J.C.M. Christianen, P.C.M. Wilson, D.A. |
author_facet | van Rhee, P.G. Rikken, R.S.M. Abdelmohsen, L.K.E.A. Maan, J.C. Nolte, R.J.M. van Hest, J.C.M. Christianen, P.C.M. Wilson, D.A. |
author_sort | van Rhee, P.G. |
collection | PubMed |
description | Stomatocytes are polymersomes with an infolded bowl-shaped architecture. This internal cavity is connected to the outside environment via a small ‘mouth’ region. Stomatocytes are assembled from diamagnetic amphiphilic block-copolymers with a highly anisotropic magnetic susceptibility, which permits to magnetically align and deform the polymeric self-assemblies. Here we show the reversible opening and closing of the mouth region of stomatocytes in homogeneous magnetic fields. The control over the size of the opening yields magneto-responsive supramolecular valves that are able to reversibly capture and release cargo. Furthermore, the increase in the size of the opening is gradual and starts at fields below 10 T, which opens the possibility of using these structures for delivery and nanoreactor applications. |
format | Online Article Text |
id | pubmed-4176683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Nature Pub. Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-41766832014-10-21 Polymersome magneto-valves for reversible capture and release of nanoparticles van Rhee, P.G. Rikken, R.S.M. Abdelmohsen, L.K.E.A. Maan, J.C. Nolte, R.J.M. van Hest, J.C.M. Christianen, P.C.M. Wilson, D.A. Nat Commun Article Stomatocytes are polymersomes with an infolded bowl-shaped architecture. This internal cavity is connected to the outside environment via a small ‘mouth’ region. Stomatocytes are assembled from diamagnetic amphiphilic block-copolymers with a highly anisotropic magnetic susceptibility, which permits to magnetically align and deform the polymeric self-assemblies. Here we show the reversible opening and closing of the mouth region of stomatocytes in homogeneous magnetic fields. The control over the size of the opening yields magneto-responsive supramolecular valves that are able to reversibly capture and release cargo. Furthermore, the increase in the size of the opening is gradual and starts at fields below 10 T, which opens the possibility of using these structures for delivery and nanoreactor applications. Nature Pub. Group 2014-09-24 /pmc/articles/PMC4176683/ /pubmed/25248402 http://dx.doi.org/10.1038/ncomms6010 Text en Copyright © 2014, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article van Rhee, P.G. Rikken, R.S.M. Abdelmohsen, L.K.E.A. Maan, J.C. Nolte, R.J.M. van Hest, J.C.M. Christianen, P.C.M. Wilson, D.A. Polymersome magneto-valves for reversible capture and release of nanoparticles |
title | Polymersome magneto-valves for reversible capture and release of nanoparticles |
title_full | Polymersome magneto-valves for reversible capture and release of nanoparticles |
title_fullStr | Polymersome magneto-valves for reversible capture and release of nanoparticles |
title_full_unstemmed | Polymersome magneto-valves for reversible capture and release of nanoparticles |
title_short | Polymersome magneto-valves for reversible capture and release of nanoparticles |
title_sort | polymersome magneto-valves for reversible capture and release of nanoparticles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176683/ https://www.ncbi.nlm.nih.gov/pubmed/25248402 http://dx.doi.org/10.1038/ncomms6010 |
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