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Estimating autozygosity from high-throughput information: effects of SNP density and genotyping errors
BACKGROUND: Runs of homozygosity are long, uninterrupted stretches of homozygous genotypes that enable reliable estimation of levels of inbreeding (i.e., autozygosity) based on high-throughput, chip-based single nucleotide polymorphism (SNP) genotypes. While the theoretical definition of runs of hom...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176748/ https://www.ncbi.nlm.nih.gov/pubmed/24168655 http://dx.doi.org/10.1186/1297-9686-45-42 |