OncomiR-196 promotes an invasive phenotype in oral cancer through the NME4-JNK-TIMP1-MMP signaling pathway

BACKGROUND: MicroRNA-196 (miR-196), which is highly up-regulated in oral cancer cells, has been reported to be aberrantly expressed in several cancers; however, the significance of miR-196 in oral cancer has not yet been addressed. METHODS: Cellular functions in response to miR-196 modulation were e...

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Detalles Bibliográficos
Autores principales: Lu, Ya-Ching, Chang, Joseph T, Liao, Chun-Ta, Kang, Chung-Jan, Huang, Shiang-Fu, Chen, I-How, Huang, Chi-Che, Huang, Yu-Chen, Chen, Wen-Ho, Tsai, Chi-Ying, Wang, Hung-Ming, Yen, Tzu-Chen, You, Guo-Rung, Chiang, Chang-Hsu, Cheng, Ann-Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176851/
https://www.ncbi.nlm.nih.gov/pubmed/25233933
http://dx.doi.org/10.1186/1476-4598-13-218

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