The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action

BACKGROUND: This study aimed to evaluate the prophylactic effect of goshajinkigan (GJG) on paclitaxel (PTX)-induced neuropathy and to elucidate the mechanism of action. RESULTS: There was a time-dependent irreversible decrease in pain threshold in PTX group. In PTX/GJG group, pain threshold showed c...

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Detalles Bibliográficos
Autores principales: Matsumura, Yukiko, Yokoyama, Yoshihito, Hirakawa, Hachidai, Shigeto, Tatsuhiko, Futagami, Masayuki, Mizunuma, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176860/
https://www.ncbi.nlm.nih.gov/pubmed/25240613
http://dx.doi.org/10.1186/1744-8069-10-61

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