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Activity-dependent regulation of astrocyte GAT levels during synaptogenesis

Astrocytic uptake of GABA through GABA transporters (GATs) is an important mechanism regulating excitatory/inhibitory balance in the nervous system, however mechanisms by which astrocytes regulate GAT levels are undefined. Here we show at mid-pupal stages the Drosophila CNS neuropil is devoid of ast...

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Detalles Bibliográficos
Autores principales: Muthukumar, Allie K., Stork, Tobias, Freeman, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176984/
https://www.ncbi.nlm.nih.gov/pubmed/25151265
http://dx.doi.org/10.1038/nn.3791